A Relentless Passion for Healing
We are Sonoma. We change lives for the better.
And by changing lives for the better, we better ourselves.
Sonoma Pharmaceuticals is a global healthcare leader developing and producing stabilized hypochlorous acid (HOCl) products for a wide range of applications, including dermatological conditions, wound care, animal health care, eye care, nasal care and oral care.
Microcyn® Technology
Natural body ingredients that boost your immune system
Tightly controlled chemistry resulting in unmatched stability. Our Microcyn® technology is based on one of the body’s most important molecules: Hypochlorous acid (HOCl).
Launched in 2004, it was the first revolutionary stable patented HOCl formulation in a bottle. With virtually no side effects or contraindications, you can utilize our solutions as often as needed to cleanse skin, relieve irritations and restore your well-being and peace of mind.
Microcyn® Technology – Safe as water
In-vitro and clinical studies of Hypochlorous Acid (HOCl) show it to have impressive antipruritic, antimicrobial and anti-inflammatory properties. The Microcyn® Technology not only optimizes HOCl for superior efficacy and safety, it guarantees potency for the life of the product. With virtually no side effects or contraindications, you can utilize Microcyn®-based products as often as needed to cleanse skin, relieve irritations and restore your well-being and peace of mind.
- Cleanse
- Relieve
- Restore
TRIPLE MODE OF ACTION
3x
Based on one of the body’s most important molecules, Hypochlorous acid (HOCl), Microcyn® Technology has a Triple Mode of Action and profound impact on infection, inflammation and scarring:
Anti-microbial
In-vitro and clinical studies of Microcyn Technology breaks down the biofilm along with having impressive anti-pruritic, anti-microbial, anti-viral and anti-inflammatory properties.
Anti-inflammatory
A powerful anti-inflammatory, our products treat common conditions while reducing infections, itch, pain, scarring and harmful inflammatory responses.
Regenerative
A gentle and safe solution that increases blood/oxygen flow to the wound, resulting in faster, more effective healing.
Microcyn® Technology Applications
Cleanse
Safely eradicates biofilm and other irritants.
Greater than 99% reduction in killing 23 different microorganisms
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Complex structure of microorganisms that generate a protective shell, allowing bacteria to collect and proliferate
Relieve
Reduces inflammation, pain, itch and swelling fast.
Study 1: Open-Label Study2
Open-label, single-arm study over 7 days
Results
HOCl rapidly reduces pruritus in mild-to-moderate atopic dermatitis (AD)
Study 2: Randomized, Blinded, Controlled Study3
- 72-hour study
- Treated group (n=19): HOCl BID
- Untreated group (n=10): No treatment
Results
The mean pruritus VAS scores saw a greater improvement among the treated group than the untreated group between baseline and 72 hours post application
- Prevents allergen and calcium-induced mast cell degranulation for up to 8 hours after a single exposure in vitro
- Reduces wound inflammation that inhibits healing
- Stabilizes the mast cell membrane to inhibit the cell machinery for granule secretion, while not altering the signal transduction pathways or calcium mobilization
- Inhibits degranulation stimulated by antigen or calcium ionophore
*A23187 + PMA is a calcium ionophore; †b-hexosaminidase is a marker of IgE-antigen-induced mast cell degranulation.
Restore
Increasing oxygen to the area in need helps accelerate the body’s natural healing process.
Increases Oxygenation5
Assists Wound Healing6
Wound healing involves a complex sequence of events. Fibroblasts are the primary synthetic cells in the repair process of most structural proteins used during tissue reconstruction.
At lower concentrations of HOCl, the percentage of fibroblast migration exceeded that of the control at 24 hours.
Effect of HOCl on Skin Fibroblast Cell Migration in a Wound Healing Assay
Microcyn® Technology is suitable for the following indications
Unique chemistry
The main component, hypochlorous acid (HOCl), is naturally produced as part of our immune system during phagocytosis. When neutrophils encounter bacteria or other pathogens, the neutrophils engulf it, generate HOCl and instantly destroys the microorganism. This process is called the “oxidative burst”.
During the activation of neutrophils, ‘respiratory bursts’ generate hydrogen peroxide (H2O2) and the activated granule enzyme myeloperoxidase converts H2O2 into hypochlorous acid (HOCl).
